Nisku is a hamlet and an industrial/business park in Alberta, Canada within Leduc County. It has an elevation of 705 metres (2,313 ft).
The hamlet and industrial/business park are located in census division No. 11 and in the federal riding of Edmonton—Wetaskiwin.
The Hamlet of Nisku is located east of the intersection of Queen Elizabeth II Highway (Highway 2) and Highway 625, between the cities of Edmonton and Leduc. More specifically, the hamlet is located within an industrial/business park on the north side of Highway 625 (20 Avenue) between Sparrow Drive and the Canadian Pacific Railway.